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A team of researchers at Tecnológico de Monterrey in Mexico have unveiled a novel method for creating nanoparticles that could revolutionize burn treatment. This innovative approach combines natural polymers, specifically those found in shrimp shells, with various metals to produce thin films with significant therapeutic potential.
Harnessing Chitin
The team focused on utilizing substances like chitin, a polysaccharide present in the exoskeletons of insects and crustaceans, including shrimp.
The transformation of chitin into chitosan, achieved through chemical or enzymatic modification, opens the door to creating films akin to transparent plastic. To enhance these films, micro and nanometric levels of metals such as gold, silver, copper, or metallic salts like barium, strontium titanate, and zinc oxide are incorporated.
A Unique Approach to Burn Treatment
The team conducted experiments involving induced first and second-degree burns in Wistar rats. Following stringent medical protocols and ethical animal treatment practices, patches of the developed film were applied with precise nanoparticle concentrations. This approach aimed at fostering cell regeneration while avoiding bacterial contamination and preserving healthy cells.
Abundant Raw Material from Shrimp Waste
Highlighting the abundance of raw materials, Dr. Gabriel Luna Bárcenas, a distinguished professor in biomaterials, pointed out that Mexico boasts over 100 shrimp companies generating hundreds of tons of waste. This waste serves as the primary resource for the development of these innovative composite materials, offering an easily accessible and environmentally friendly solution.
Moving Towards Clinical Testing
While burn treatment films are not yet in the preclinical phase for human testing, Dr. Bárcenas expressed optimism about reaching this milestone soon. The promising results of their research suggest a potential breakthrough in burn care, offering new hope for more effective and advanced treatment methods.